I found the experience particularly valuable this year as the talks allowed me to gauge what the Gatsby supported PhD students had achieved after one year, two years or even three/ four years. This helped to give me an idea of the rate of progress expected from me when I start my PhD in October. The stand-out talk for me however, was given by Professor Hagen Bailey, of the Department of Chemistry at the University of Oxford. Completely eschewing a plant science theme, he described how "nanopore" technology could revolutionise DNA sequencing. This technique involves introducing membrane pores based on alpha-hemolysin from Staphyloccus into a chip, and feeding DNA through these channels. By incorporating a nuclease which cleaves off bases one by one as the DNA strand emerges or inserting a base reader into the channel itself, the sequence can be read. This avoids the need for using fluorescent bases (required for most sequencing methods) and can be fashioned into arrays with thousands of pores, ultimately capable of sequencing the human genome in 10 minutes. Given that this would be the equivalent of reading a thousand copies of War and Peace, this is quite impressive! Professor Hagen also described how these pores could be used to connect aqueous droplets to form "minimal tissues", which could have potential in organ enhancement or replacement. An intriguing diversion from plant science and an exciting topic to follow in the future...
I must confess that I do enjoy the "Oxford experience" that the meeting gives me - staying in quirky college rooms (no piano this time, but still lots of random doors and a fireplace), listening to the clock bells chiming out over the city at night, the formal evening dinner... I did feel sorry for the vegetarians this year however, who instead of being served "prawn and avocado cocktail" had to make do with "avocado...and more avocado ". I'm already looking forward to the next meeting, and who knows? Perhaps I will be presenting something myself...